38. A patient with chronic heart failure takes an ACE inhibitor and a beta-blocker. From a medicinal perspective, what is the technical pathophysiological rationale for using a beta-blocker in chronic heart failure?

  • To increase heart rate.
  • To block the effects of sympathetic nervous system activation, reducing myocardial oxygen demand and improving cardiac remodeling.
  • To increase preload.
  • To dilate peripheral blood vessels.
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